Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing
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چکیده
منابع مشابه
P 70: Primary Progressive MS and Affecting Genes
Multiple sclerosis is a CNS autoimmune disease configured by demyelination, inflammation, and degeneration of axons. This disease inflict great harms to patients. The most common problem is inability to control musculoskeletal system and decrease in mobility. These consequences could vary from patients to patients. About 10-15% of all MS patients develop primary progressive MS (PPMS). Despite t...
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Insulators are DNA sequence elements that can serve in some cases as barriers to protect a gene against the encroachment of adjacent inactive condensed chromatin. Some insulators also can act as blocking elements to protect against the activating influence of distal enhancers associated with other genes. Although most of the insulators identified so far derive from Drosophila, they also are fou...
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Chromatin remodeling contributes to healthy adaptations, including learning and memory, and to diseases, including schizophrenia. Dr. Eric Nestler and colleagues at the University of Texas Southwestern Medical Center and Harvard Medical School revealed its role in cocaine pathology. In a series of experiments with rats, they demonstrated that cocaine-induced chromatin remodeling increases the p...
متن کاملp 70: primary progressive ms and affecting genes
multiple sclerosis is a cns autoimmune disease configured by demyelination, inflammation, and degeneration of axons. this disease inflict great harms to patients. the most common problem is inability to control musculoskeletal system and decrease in mobility. these consequences could vary from patients to patients. about 10-15% of all ms patients develop primary progressive ms (ppms). despite t...
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ژورنال
عنوان ژورنال: Virology Journal
سال: 2007
ISSN: 1743-422X
DOI: 10.1186/1743-422x-4-85